Assessment of Osseointegration Properties of Hyaluronic Acid coated Titanium Implant Versus Sandblasted Large Thread Acid Etched Implants in Posterior Maxilla. A Randomized Clinical Trial

Document Type : Original Article

Authors

1 Lecturer, oral surgery & anesthesia department, faculty of dentistry, MSA University, Giza, Egypt

2 Associate professor of periodontology, faculty of Dentistry, Fayoum University, MSA University

3 Lecturer of periodontology, faculty of Dentistry, MSA University

4 Department of oral & maxillofacial surgery .MSA university

10.21608/msadj.2024.301280.1040

Abstract

Background and Aim: This study was aimed to compare the implant stability of Hyaluronic Acid coated implants with Sandblasted Large Thread Acid Etched surface implants placed in the maxillary posterior area. Methods: 30 Adults patients with at least one missing maxillary posterior tooth were randomly assigned into two equal parallel groups with a 1:1 allocation ratio to receive either HA coated Titanium Implant (test group) or SAE Implants (control group). Outcomes measured: The primary outcome was implant stability as measured by the Resonance Frequency Analysis (RFA) via the Osstell ISQ system ® at baseline (T0) and 6 (T1) and 12 (T2) weeks post-operatively. The secondary outcome measured involved surgical wound healing based on Landry index evaluated at 7th and 14th day post-operatively. Results: Regarding implant stability, results of the primary implant stability at (T0) revealed no statistically significant differences between the two study groups (P= 0.129). Contrarily, the secondary implant stability at (T1) and (T2) weeks showed statistically significant greater ISQ values in the HA coated implant group than SAE implants group (P≤0.001 at T1and T2). On the 14th postoperative day, the surgical wound healing in the HA coated Implant group was either very good or excellent, while in SAE implants group varied from good to excellent soft tissue healing. The differences in soft tissue index were statistically significant between the two groups (P=0.005). Conclusion: HA-coated implants with hydrophilic surfaces achieve faster osseointegration than those without modification within a shorter period, making them suitable candidates for early loading protocols.

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